25 year old developer and startup guy living in SF
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If you've ever tried to tinker with something in Vista and received a "you need permission to perform this action" warning, you know how frustrating it can be. Vista's new found "security" locks down a lot of things even if your user account has administrative privileges. I ran into a problem like this when installing Adobe Acrobat Reader 8 where the installer didn't have the permissions to run it's own exe file, or something like that.

For this example, I'll be giving my user account full read/write permissions for a random file. Again, this is just an example and I have no idea why you would ever need full read/write permissions for such a random file. The point is to show you how to overcome a "you need permission to perform this action" situation if you ever find yourself in it. Bookmark the page as you might need it down the road.
That's generally how the process goes. You don't want to be doing this too often though. Should you ever get a virus in Vista, the files thought to have been protected, which you gave your account full permissions for, could easily be destroyed - not good if that's a critical system file. This probably also works in XP but I haven't used XP in a while. Vista is just a lot more protective about things so you probably never had this type of situation in Vista, or at least I haven't.
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